Description
This system allows profiling of RNA and protein expression from distinct tissue compartments and cell populations with an automated and scalable workflow that integrates with standard histology staining.
Technical Specifications
Up to 8 slides/day (at 12 ROIs per slide, 10 mm by 10 mm scan area)
Minimum 10 μm diameter UV illumination area
20 x 0.45 NA objective resolution
4 fluorescent channels: (FITC/SYTO13/AF488), (CY3/AF532/PE/SYTO83), (TxRed/AF594), (CY5/AF647/Dylight 650)
Four 1 x 3 inch slide capacity
8TB (> 300 10 mm x 10 mm 4 channel slide images) data storage capacity
Data visualisation and analysis:
• Intuitive and interactive interface that automatically connects quantitative readout with spatial information
• Workflow includes QC and normalization
• Visualization include clusters, heatmaps, volcano plots, bar graphs, box plots, strip plots, scatter plots, correlation plots
Model
GeoMx DSP
Manufacturer
Nanostring Technologies Ltd
Application
Spatial multiomic platform for analysis of FFPE and fresh frozen tissue sections
Special Remarks
Spatial imaging systems are placed in Spatial Anlytics Lab at level 12 N as part of deep sapatial imaging program in CSI.
Location
Cancer Science Institute, Microscopy & Multiplex Assays Core
NUS Medicine MD6 Centre for Translational Medicine
12-01A North, Spatial Analytics Lab
14 Medical Dr, Singapore 117599
Booking Information
Charges: N/A
Service or Self-operated: Service required
Website for booking: https://csi.nus.edu.sg/staff-access/
Key Contact(s)
Chen Qiaojing
qj_chen@nus.edu.sg
Biology | Cell and Tissue Work | CSI | Equipment